Holistic DEPRESSION Treatment

We are a medical clinic specialising in the holistic treatment of Depression and multi symptom chronic conditions. Download our Holistic Treatment Guide to see how we help you get better

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World Leaders in Holistic Care

Our team led by world-leading expert Dr Dani Gordon specialises in treating multi symptom chronic conditions including Depression. These conditions respond poorly to pharmaceuticals alone, often leading to ineffective treatment and frustrated patients. Our mission is to improve your resilience and quality of life, even when a cure is not possible, through personalised holistic treatment programs combining:
  • Drug therapy 
  • Novel medicines 
  • Nutritional medicine 
  • Mindbody medicine
  • Functional medicine

Holistic Depression Treatment

About Depression and Low Mood

Depression is a complex illness and can look different from one person to the next. It is incredibly common and can range in severity but even the milder forms can have a huge negative impact on daily life.

Depression Symptoms

Depression can include symptoms such as:

  • Feeling down, depressed or hopeless
  • Little interest or pleasure in doing things
  • Fatigue
  • Slowed down physically or the opposite agitated
  • Trouble getting motivated
  • Social withdrawal
  • Negative thoughts
  • Feelings of Overwhelm with decision making
  • Appetite changes–eg craving carbs or the opposite–having no appetite
  • Low energy
  • Sluggish thinking, poor concentration
  • Feelings of excessive guilt or worthlessness
  • Disrupted sleep-sleeping too much or waking up in the early morning
  • Suicidal thoughts or acts

What Causes Depression

The reasons for why someone gets depressed are multifactorial and complex and slightly different for each person but involve cognitive brain neural networking, genetics, environment and physiological factors such as hormones, inflammatory chemicals and sleep wake cycle regulation. Lifestyle factors such as sleep, exercise and diet can also play a role. The role of stress and its relationship to affecting our microbiome is another emerging factor in depression etiology.

Kindling in Chronic Depression

Often as the lead up to the initial episode, significant stressors are involved and in recurrent depression, vulnerability to repeats seems to increase due to a brain-driven process called kindling, involving central nervous system dysfunction and brain networks, decreased neuroplasticity (the ability of the brain to build new cells and adapt) and more sleep dysfunction such as decreased slow wave sleep.

Chronic Illness & Depression

If you suffer from a chronic illness or chronic pain, these conditions can also cause depression as a result of your illness or illness experience or make existing depression worse. Conditions such as chronic pain from any source, neurological disorders, fibromyalgia and chronic fatigue syndrome/ME all increase the risk of depression and can go and hand in hand.

Our Approach To Depression

A personalised holistic approach to treating depression is the most effective way to recover, since two people with the same diagnosis of depression may respond to different things including medicines, nutritional medicine, mindbody, microbiome and lifestyle interventions tailored to them specifically. Novel medicines can be incredibly helpful in those who suffer with what is known as ‘treatment resistant depression’ where the standard medications and psychotherapy approaches have not been effective and can also help with fatigue, sleep disturbance, anxiety and motivation.

  • Diet for Depression – Although depression is not a straightforward nutrition illness, certain types of diets may influence and improve depression symptoms according to emerging research, due possibly to the mood effects of altering the microbiome as well as affecting neurotransmitter levels. Although not a cure, personalizing the dietary approach appears to be important and combining any dietary intervention with other treatments.
  • Mindbody treatment for depression – Because many people with depression also suffer from anxiety, relaxation response techniques can help lower stress and anxiety levels which may also help depression indirectly where other techniques have ben shown to have a direct antidepressant effect. CBT can be very helpful, especially for certain subtypes of depression known as ‘cognitive affective’ type but does not work for everyone. Specific forms of exercise can also help too by stimulating endorphin release. To be most effective, the mindbody techniques should be tailored to each patient using a holistic approach and combined with other treatments.
  • Functional Medicine Testing for depression – From stress tolerance and resilience testing to looking at the gut microbiome for mood related markers and looking at inflammatory biomarkers and circadian rhythm dysfunction, functional medicine testing can also play a role in our approach.

Our Process

Step 1.
Rapid Symptom Relief With Novel Medicines

Novel botanical medicines influence multiple biological functions and often bring rapid relief of symptoms within days.

Most patients see a significant improvement within the first month of therapy across multiple symptom clusters including mood, fatigue, stress, pain, sleep and mental function. 

Novel Medicines Can Dramatically improve Quality Of Life

Many patients are able to wean down on other medications to help to further improve symptoms and quality of life and reduce unnecessary drug side effects.

Step 2.
Long Term Recovery

Once initial symptoms are relieved, we develop a personalized holistic long-term treatment plan, since even two people with the same diagnosis can need different things.  This can include:

  • Drug therapy – 
  • Functional medicine testing – advanced tests to identify root causes of symptoms such as microbiome testing, brain-gut axis function, methylation pathways and hormone levels 
  • Nutritional medicine –  personalized therapeutic diets, supplements and botanicals.
  • Mindbody medicine – meditation, relaxation response training, biofeedback.
  • Lifestyle medicine – sleep, exercise, work/home environment.

Step 3.
Long Term Resilience

Resilience is the ability to adapt and bounce back in the face of challenging circumstances.

The ability to reduce distress, both mentally and physically enhances your quality of life & activates our inner potential for healing.  Resilience can always be improved regardless of your medical diagnoses. 

Our virtual platform gives you access to holistic tools and resources as part of your treatment to enhance your resilience further, manage your holistic health & see your progress over time so you can get better and stay better.

About Dr Dani Gordon MD

Dr Gordon is a London based double board certified medical doctor and world leading authority in Integrative and Cannabinoid Medicine.

She is considered the UK’s most experienced cannabis clinician having trained many of the UK’s cannabis doctors and treated 1000s of patients with medical cannabis with over a decade of clinical experience in integrative & cannabinoid medicine for the treatment of chronic illness.

She has spoken at the UN, delivered medical cannabis practice recommendations to Downing Street, is a Founding member and vice-chair of the UK Medical Cannabis Clinicians Society, Policy Advisor for the Conservative Drug Policy Reform Group and has been featured in the Sunday Times, The Guardian, BBC News, Channel 4, Vogue and Marie Claire.

She is the author of the CBD Bible a Guide to Medical Cannabis and The Resilience Blueprint.


Download the guide to learn how holistic treatment with novel medicines could help you get better.


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